4th Generation HIV Test

Dr.Deyn Natthakhet Yaemim MD, Last reviewed 28 January 2020


HIV 4th Generation Test.

Modern HIV tests at PULS clinic are very accurate within the time limits that they are recommended. A 4th generation HIV test (HIV-1 p24 antigen Ag/HIV-1 antibody and HIV-2 antibody) does detect antibody for HIV-1 and HIV-2, and HIV-1 p24 antigen. It  will detect 95% of infections at 28 days after exposure and it will detect more than 99.99% of infections at three months. If you are worried you can repeat at 3 months time to be 99.99+0.01% sure.


The 4th generation HIV test, detects the HIV antibody (Ab) and p24 antigen (Ag), giving a window period of 1 month (28 days) from exposure to reliable test result.


FDA-Approved HIV Antibody Test

PULSE Clinic standard HIV test is the HIV 4th Generation Antigen/Antibody Test. This FDA-approved 4th generation HIV test evaluates the blood for HIV Type 1 and Type 2 in two ways: By detecting antibodies that your immune system creates specifically to fight the HIV virus, as well as detecting Human Immunodeficiency Virus antigens called HIV P24 antigens. These antigens are viral proteins that make up most of the core of the virus; they are especially helpful in diagnosing HIV because these antigen levels P24 antigens are high in the first few weeks after infection. Since this test is sensitive to P24 antigens, it is useful for diagnosing HIV infections when antibody levels are still initially low. If your initial blood test result is positive, a confirmation test will be completed on the same blood sample to confirm the diagnosis at no additional cost. Getting tested for HIV is essential– It is possible to have HIV and infect your partner without showing any signs or symptoms of having the virus.

All laboratory testing, including STD tests, accuracy rates are measured in terms of sensitivity and specificity. Our FDA-approved HIV 4th generation antibody/antigen test has a sensitivity rate of 100% and a specificity of 99.72-100%.

4th Generation HIV Testing Process

Testing process

Sample Required


Waiting Time

5 minutes

Small blood sample


1 day

5 minutes

Small blood sample


15 minutes



What do I need to do to prepare for the test?

No fasting or additional preparation is needed for the HIV Antibody blood test.

When is the right time to get the HIV Antibody Test?

The right time to take our 4th Generation HIV Antibody / Antigen Test is 2-3 weeks after exposure. Our blood test searches for the presence of these antibodies in the blood, as well as antigens on the surface of the HIV virus. Most people will develop detectable antibodies (proteins made by the immune system to fight the HIV virus) within this time frame, but in rare cases it may take up to 3 months for them to develop. This test is sensitive to P24 antigens, so it is useful for diagnosing HIV infections when antibody levels are still initially low. We do recommend retesting after three months have past since potential exposure for conclusive results. If antibodies or antigens to HIV are found, a supplemental differentiation assay is performed at no additional cost to confirm the presence of HIV. If you are concerned about recent exposure, our HIV RNA Early Detection Test can detect the presence of HIV as early as 9-11 days after exposure.

What will the test results say?

Your HIV test results will say either positive or negative. There are no signs of HIV antibodies or antigens in the blood if the result is negative. If positive, HIV antibodies were found, and a confirmation test will be completed on the same blood sample to confirm the diagnosis at no additional cost.

Can HIV be cured or treated?

No, there is no cure for HIV, but with the help of various anti-retroviral drugs, HIV can be managed and individuals with HIV can lead normal lives. The medications prescribed to treat and manage HIV strengthen the immune system and help prevent HIV from developing into AIDS.

Who needs HIV Antibody testing?

HIV affects both men and women. Anyone who has had unprotected sex or who engages in intravenous drug use should get tested. It is possible to have HIV for a long time without being aware, especially because its symptoms (if present) could be mistaken for other illnesses. The only way to know is to get tested. The HIV test should be a part of your routine STD screening.

Book an appointment with PULSE clinic

PULSE Clinic has major campuses in Central Hong Kong, Hong Kong island; Central Kuala Lumpur (Bukit Bintang), Malaysia; Center Silom), Bangkok; and Center Sukhumvit, Bangkok, Thailand. For appointment booking and more information, choose your location below:

60/4 Silom Road, Suriyawong, Bangkok

BTS Sala Daeng Exit 3, MRT Silom Exit 2
Tel: +6626525097, +66652371936  

Email: info.silom@pulse-clinic.com

OPEN DAILY  · Mon - Sun·  10AM - 7:00PM   

· Book An Appointment @ Silom ·  

Trendy Building, Sukhumvit 13, Bangkok 

Tel: +6621687459, +66959156385  

Email: info.nana@pulse-clinic.com

OPEN DAILY  ·  10AM - 7:00PM 
· Book An 
Appointment @ Sukhumvit ·

127/2 Ratuthit Songroipi Rd, Pa Tong, Phuket
Tel: +6676633368, +66952615282

Email: info.phuket@pulse-clinic.com

MONDAY  ·  10AM - 7.30PM  Emergency PEP,

                        Refill Medication only 

TUE - SAT  ·  10AM - 7:30PM Full Services 

· Book An Appointment @ Phuket ·  

61A, Jalan Sultan Ismail, Bukit Bintang, 50250
Tel: +60321102122 , +601165388678

Email: info.kl@pulse-clinic.com

MONDAY - FRIDAY  ·  11.00 AM - 07.30 PM

SAT ·  11.00 AM - 05.30 PM

· Book An Appointment  @ Kuala Lumpur ·

2F, 83 Wellington St, Central, Hong Kong
Tel: +85223898250 
Email: info.hk@pulse-clinic.com

                               OPEN MONDAY - FRIDAY  ·  11AM-7:30PM
                            · Book An Appointment @ Hong Kong


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