&lt;h1&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Bone Metastasis: Symptoms, Causes &amp;amp; Treatment&lt;/strong&gt;&lt;/span&gt;&lt;/h1&gt;
&lt;hr /&gt;
&lt;p data-path-to-node=&quot;0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong data-path-to-node=&quot;0&quot; data-index-in-node=&quot;0&quot;&gt;Bone metastasis&lt;/strong&gt; occurs when cancer cells detach from their original site and migrate to the skeletal system. While &quot;metastasis&quot; refers to any cancer that has spread, &quot;bone metastasis&quot; specifically describes the presence of cancer in one or more areas of the bone.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong data-path-to-node=&quot;1&quot; data-index-in-node=&quot;0&quot;&gt;Where and Why It Occurs&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p data-path-to-node=&quot;2&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Though virtually any cancer can spread to the bones, it is most common in patients with &lt;strong data-path-to-node=&quot;2&quot; data-index-in-node=&quot;88&quot;&gt;breast or prostate cancer&lt;/strong&gt;. These secondary tumors can appear in any bone, but they are most frequently found in:&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li data-path-to-node=&quot;3,0,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;The spine&lt;/span&gt;&lt;/li&gt;
&lt;li data-path-to-node=&quot;3,1,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;The pelvis&lt;/span&gt;&lt;/li&gt;
&lt;li data-path-to-node=&quot;3,2,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;The thigh bones (femur)&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p data-path-to-node=&quot;4&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;In some cases, bone pain or a fracture is the very first indication of an undiagnosed cancer. In others, these metastases may not appear until years after the initial cancer treatment.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong data-path-to-node=&quot;5&quot; data-index-in-node=&quot;0&quot;&gt;Symptoms and Outlook&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p data-path-to-node=&quot;6&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Bone metastasis often leads to significant pain and an increased risk of fractures. While it is rarely possible to fully cure cancer once it has reached the bones, various treatments are available to manage symptoms, reduce pain, and improve quality of life.&lt;/span&gt;&lt;/p&gt;
&lt;p data-path-to-node=&quot;6&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Bone Metastasis Symptoms&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p data-path-to-node=&quot;0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;In many cases, bone metastasis may not present any immediate symptoms. However, when they do occur, they typically manifest as follows:&lt;/span&gt;&lt;/p&gt;
&lt;h3 data-path-to-node=&quot;1&quot;&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong data-path-to-node=&quot;1&quot; data-index-in-node=&quot;0&quot;&gt;Common Physical Symptoms&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;ul&gt;
&lt;li data-path-to-node=&quot;2,0,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong data-path-to-node=&quot;2,0,0&quot; data-index-in-node=&quot;0&quot;&gt;Bone Pain:&lt;/strong&gt; Persistent aching or sharp pain in the affected area.&lt;/span&gt;&lt;/li&gt;
&lt;li data-path-to-node=&quot;2,1,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong data-path-to-node=&quot;2,1,0&quot; data-index-in-node=&quot;0&quot;&gt;Fractures:&lt;/strong&gt; Weakened bones that break easily or unexpectedly.&lt;/span&gt;&lt;/li&gt;
&lt;li data-path-to-node=&quot;2,2,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong data-path-to-node=&quot;2,2,0&quot; data-index-in-node=&quot;0&quot;&gt;Hypercalcemia:&lt;/strong&gt; High calcium levels in the blood, which can lead to nausea, vomiting, constipation, and mental confusion.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;h3 data-path-to-node=&quot;3&quot;&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong data-path-to-node=&quot;3&quot; data-index-in-node=&quot;0&quot;&gt;Spinal Metastasis Symptoms&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p data-path-to-node=&quot;4&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;When cancer spreads to the spine, it can compress the spinal cord, leading to specific neurological issues:&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li data-path-to-node=&quot;5,0,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong data-path-to-node=&quot;5,0,0&quot; data-index-in-node=&quot;0&quot;&gt;Neck and Back Distress:&lt;/strong&gt; Significant pain, stiffness, or pressure.&lt;/span&gt;&lt;/li&gt;
&lt;li data-path-to-node=&quot;5,1,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong data-path-to-node=&quot;5,1,0&quot; data-index-in-node=&quot;0&quot;&gt;Bladder and Bowel Changes:&lt;/strong&gt; This includes urinary urgency, urinary incontinence (leaking), or fecal incontinence (loss of bowel control).&lt;/span&gt;&lt;/li&gt;
&lt;li data-path-to-node=&quot;5,2,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong data-path-to-node=&quot;5,2,0&quot; data-index-in-node=&quot;0&quot;&gt;Mobility Issues:&lt;/strong&gt; Noticeable weakness in the arms or legs.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Bone Metastasis Causes&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Bone metastasis is caused by cancer that starts in one area and spreads to a bone. It&#39;s not clear why some cancers travel to the bones rather than to other common sites for metastasis, such as the liver.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;When to See a Doctor&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;If you have long-lasting symptoms that worry you, make an appointment with a doctor or other healthcare professional. If you&#39;ve been treated for cancer in the past, tell your healthcare team about your medical history and your concern about your symptoms.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;div class=&quot;aem-GridColumn aem-GridColumn--default--12 aem-GridColumn&quot;&gt;
&lt;div class=&quot;cmp-dita-title&quot;&gt;
&lt;div class=&quot;cmp-title&quot; data-testid=&quot;cmp-title&quot;&gt;
&lt;h2 id=&quot;risk-factors&quot; class=&quot; cmp-title__text--h2&quot; tabindex=&quot;-1&quot;&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Risk Factors&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;hr /&gt;&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;div class=&quot;aem-GridColumn aem-GridColumn--default--12 aem-GridColumn&quot;&gt;
&lt;div class=&quot;cmp-text__rich-content cmp-dita-content cmp-text--body-sans-medium  &quot;&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Some types of cancer have a higher risk of causing bone metastasis than others do. Cancers more likely to spread to the bones include:&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Breast cancer&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Kidney cancer&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Lung cancer&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Lymphoma&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Melanoma&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Multiple myeloma&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Prostate cancer&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Thyroid cancer&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;/div&gt;
&lt;/div&gt;

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