&lt;h2&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;Overview&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Catecholamine fractionation, free, plasma test is a diagnostic procedure used to measure the levels of catecholamines, such as dopamine, adrenaline (epinephrine), and noradrenaline (norepinephrine), in the blood plasma. This test provides valuable information about the functioning of the adrenal glands and the sympathetic nervous system. By analyzing the levels of these neurotransmitters in the plasma, healthcare providers can assess conditions such as pheochromocytoma, neuroblastoma, and certain types of autonomic nervous system disorders. The test involves collecting a blood sample and then analyzing it for catecholamine levels. This information helps in diagnosing and monitoring various medical conditions related to catecholamine imbalance.&lt;/span&gt;&lt;/p&gt;
&lt;hr /&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;WHAT IS IT USED FOR?&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;- Detecting pheochromocytoma and paraganglioma, as a complementary assessment alongside fractionated plasma and urine metanephrine tests.&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #808080;&quot;&gt;- Monitoring the diagnosis of individuals with neuroblastoma and similar tumors, as an additional evaluation alongside urine vanillylmandelic acid and homovanillic acid tests.&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #808080;&quot;&gt;- Assessing patients with autonomic dysfunction, autonomic failure, or autonomic neuropathy.&lt;/span&gt;&lt;/p&gt;
&lt;div class=&quot;w-full pt-2 md:pt-0 dark:border-white/20 md:border-transparent md:dark:border-transparent md:w-[calc(100%-.5rem)]&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;METHOD NAME&lt;br /&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)&lt;/span&gt;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;&lt;br /&gt;AVAILABILITY&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;TBC&lt;/span&gt;&lt;/p&gt;
&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;REPORTING NAME&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Catecholamine Fract, Free, P&lt;/span&gt;&lt;/p&gt;
&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;OTHER NAMES&lt;/strong&gt;&lt;/span&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Adrenaline&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Catecholamine Fractionation, Pharmacy Solution&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Catecholamines, Unconjugated&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Dopamine&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Epinephrine&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Noradrenaline&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Norepinephrine&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Pheochromocytoma&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Pressor Amines&lt;/span&gt;&lt;/p&gt;

&lt;h3 id=&quot;SpecimenType-title&quot;&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SPECIMEN TYPE&lt;/strong&gt;&amp;nbsp;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Plasma EDTA Meta&lt;/span&gt;&lt;/p&gt;
&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SHIPPING INSTRUCTIONS&lt;br /&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;TBC&lt;/span&gt;&lt;/p&gt;
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&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SPECIMEN COLLECTION&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;strong&gt;Patient Preparation:&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;1. Discontinue drugs that release epinephrine, norepinephrine, or dopamine, or hinder their metabolism, for at least one week before obtaining the specimen (see Cautions for details). If this is not possible for medical reasons, contact the laboratory and discuss whether a shorter drug withdrawal period may be possible in a particular case.&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #808080;&quot;&gt;2. Unless the purpose of the measurement is drug monitoring, discontinue any epinephrine, norepinephrine, or dopamine injections or infusions for at least 12 hours before specimen collection.&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #808080;&quot;&gt;3. The patient must refrain from eating, using tobacco, and drinking caffeinated beverages for at least 4 hours before the specimen is collected.&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;strong&gt;Supplies:&lt;/strong&gt;&amp;nbsp;Catecholamine Tubes-EDTA (T066) (tubes contain sodium metabisulfite, may come as 10-mL or 6-mL tubes, and&amp;nbsp;&lt;strong&gt;have a 6-month expiration time)&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;strong&gt;Collection Container/Tube&lt;/strong&gt;:&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;strong&gt;Preferred&lt;/strong&gt;: 10-mL Catecholamine tubes containing EDTA-sodium metabisulfite solution&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;strong&gt;Acceptable&lt;/strong&gt;: 6-mL Catecholamine tubes containing EDTA-sodium metabisulfite solution&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;strong&gt;Submission Container/Tube:&lt;/strong&gt;&amp;nbsp;Plastic vial&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;strong&gt;Specimen Volume:&lt;/strong&gt;&amp;nbsp;3 mL&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;Collection Instructions:&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;strong&gt;Note:&lt;/strong&gt;&amp;nbsp;&lt;strong&gt;If the collection instructions are not followed, falsely elevated test results are highly likely.&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;1.Drawing from an indwelling intravenous (IV) line/catheter/butterfly is required.&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #808080;&quot;&gt;2.Calm the patient by giving complete instructions and reassurance regarding the procedure.&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #808080;&quot;&gt;3.Insert an indwelling IV catheter. Flush with 3 mL of sodium chloride (NaCl) using positive pressure.&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #808080;&quot;&gt;4.Have the patient rest for 30 minutes in the supine position in a quiet room.&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #808080;&quot;&gt;5.At the end of the 30 minutes, withdraw and discard a minimum of 3 mL of blood to remove the saline from the catheter.&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #808080;&quot;&gt;6.If provocative sampling (eg, standing specimen) is required, perform the provocative maneuver immediately after obtaining the supine specimen. Obtain a standing specimen immediately.&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #808080;&quot;&gt;7.For each specimen, draw 10 mL of blood into the chilled 10 mL catecholamine tube containing EDTA-sodium metabisulfite solution. A 6 mL pink top EDTA-metabisulfite tube is an acceptable substitute.&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #808080;&quot;&gt;8.Specimens must remain at refrigerated temperature during processing and transport.&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #808080;&quot;&gt;9.Separate plasma in a refrigerated centrifuge within 30 minutes of collection.&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #808080;&quot;&gt;10.Freeze specimen immediately.&lt;/span&gt;&lt;/p&gt;
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&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
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&lt;/div&gt;

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Catecholamine Fractionation, Free, Plasma