&lt;h1&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Codeine (Dirty Sprite, Lean, Sizzurp)&lt;/strong&gt;&lt;/span&gt;&lt;/h1&gt;
&lt;hr /&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Codeine is a naturally occurring substance found in opium and is classified as an opiate. In medical practice, it serves two primary functions: as an analgesic for pain relief, frequently formulated in combination with paracetamol, and as an antitussive to suppress coughing.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Effects&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;The impact of codeine is highly subjective and depends on the amount consumed. Its effects can range from subtle pain relief and mild relaxation to feelings of euphoria or heightened excitement. When taken in high doses, specifically between 100 mg and 200 mg, codeine acts as a potent sedative.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Duration&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Onset of effect&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Varies with the form of application.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Swallowed: 15 - 90 minutes&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Snorted and rectally (suppositories): after approx. 10 minutes&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Injected: after a few seconds&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Duration of action&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Swallowed: 4 - 12 hours&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Snorted 3 - 6 hours&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Dosage&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;light: 20 - 100 mg&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;medium: 100 - 150 mg&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;strong: 150 - max. 200 mg/day&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;The effect occurs more quickly when codeine is mixed with carbonic acid and sugar. From 100 mg, a strong sedative and depressant effect can already occur. Higher doses mainly increase the risk of side effects. An increase in effect at high doses is rarely seen, as the body can only absorb limited amounts of codeine.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong&gt;Information on dosage in liquid form&lt;/strong&gt;&amp;nbsp;(e.g., syrup)&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;The information is usually given in %, which you can use to calculate the dosage as follows:&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Examples:&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;0.1%: (1mg codeine in 1ml) =&amp;nbsp;&lt;strong&gt;100mg in 1dl&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;0.2%: (2mg codeine in 1ml) =&amp;nbsp;&lt;strong&gt;200mg in 1dl&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;0.3%: (3mg codeine in 1ml) =&amp;nbsp;&lt;strong&gt;300mg in 1dl&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Appearances&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Mono- and combination preparations in the form of tablets, capsules, pastilles, drops or syrup, rarely in suppositories.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;A mixture of codeine, crushed candy in sweet drinks (often lemonade) is called Lean, Texas Tea, Purple Drank, or Sizzurp.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Risks&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p data-path-to-node=&quot;2&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;span class=&quot;&quot;&gt;The use of codeine can lead to a variety of side effects,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; including:&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li data-path-to-node=&quot;3,0,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong class=&quot;&quot; data-path-to-node=&quot;3,0,0&quot; data-index-in-node=&quot;0&quot;&gt;Common Physical Reactions:&lt;/strong&gt;&lt;span class=&quot;&quot;&gt; Nausea,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; vomiting,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; dizziness,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; itching,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; and increased sweating.&lt;/span&gt;&lt;/span&gt;&lt;/li&gt;
&lt;li data-path-to-node=&quot;3,1,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong class=&quot;&quot; data-path-to-node=&quot;3,1,0&quot; data-index-in-node=&quot;0&quot;&gt;Systemic Effects:&lt;/strong&gt;&lt;span class=&quot;&quot;&gt; Constipation,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; dry mouth,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; headaches,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; loss of appetite,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; abdominal cramping,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; a slowed pulse,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; and sleep disturbances.&lt;/span&gt;&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p data-path-to-node=&quot;4&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;span class=&quot;&quot;&gt;At higher dosages,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; or when combined with other depressants,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; the risks escalate significantly.&lt;/span&gt;&lt;span class=&quot;&quot;&gt; These severe effects may include a loss of sensation,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; profound drowsiness leading to unconsciousness,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; visual impairments,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; and a life-threatening state of shock.&lt;/span&gt;&lt;span class=&quot;&quot;&gt; Most critically,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; breathing can become dangerously slow or shallow,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; potentially resulting in total respiratory arrest.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Long-Term Consequences and Dependency&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p data-path-to-node=&quot;7&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Chronic use of codeine often leads to the development of &lt;strong data-path-to-node=&quot;7&quot; data-index-in-node=&quot;57&quot;&gt;tolerance&lt;/strong&gt;, where the body habituates to the substance and the desired effects diminish over time.&lt;/span&gt;&lt;/p&gt;
&lt;p data-path-to-node=&quot;8&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Regular consumption can also lead to &lt;strong data-path-to-node=&quot;8&quot; data-index-in-node=&quot;37&quot;&gt;physical and psychological dependence&lt;/strong&gt;. Should an addiction develop, withdrawal may involve:&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li data-path-to-node=&quot;9,0,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Intense cravings for opioids and heightened anxiety or agitation.&lt;/span&gt;&lt;/li&gt;
&lt;li data-path-to-node=&quot;9,1,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Gastrointestinal distress such as nausea, vomiting, and diarrhea.&lt;/span&gt;&lt;/li&gt;
&lt;li data-path-to-node=&quot;9,2,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Physical symptoms like sneezing, a runny nose, and insomnia.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Tolerance Loss and Overdose Danger&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p data-path-to-node=&quot;12&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;It is vital to understand that after a period of withdrawal or abstinence, the body&#39;s tolerance to opioids is lost. This means the individual becomes as sensitive to the drug as they were before their dependency began. If a person resumes use at their previous dosage level without a drastic reduction, the risk of a fatal overdose is exceptionally high.&lt;/span&gt;&lt;/p&gt;
&lt;p data-path-to-node=&quot;12&quot;&gt;&amp;nbsp;&lt;/p&gt;

&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Harm Reduction Strategies&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Dangerous Combinations&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p data-path-to-node=&quot;2&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;span class=&quot;&quot;&gt;Avoid mixing opioids with other depressants,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; particularly those that suppress breathing.&lt;/span&gt;&lt;span class=&quot;&quot;&gt; This includes &lt;/span&gt;&lt;strong class=&quot;&quot; data-path-to-node=&quot;2&quot; data-index-in-node=&quot;103&quot;&gt;alcohol, cannabis, benzodiazepines, sleep aids, GHB/GBL, and antihistamines&lt;/strong&gt;&lt;span class=&quot;&quot;&gt;.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p data-path-to-node=&quot;3&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;span class=&quot;&quot;&gt;A specific warning applies to &lt;/span&gt;&lt;strong class=&quot;&quot; data-path-to-node=&quot;3&quot; data-index-in-node=&quot;30&quot;&gt;&quot;Sizzurp&quot;&lt;/strong&gt;&lt;span class=&quot;&quot;&gt; (codeine cough syrup mixtures):&lt;/span&gt;&lt;span class=&quot;&quot;&gt; the addition of carbonation and high sugar content makes the codeine harder to dose accurately and causes the effects to hit much faster and more intensely.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Guidelines for Safe Use&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p data-path-to-node=&quot;6&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Opiates are powerful medications that should only be utilized for short durations and ideally under medical supervision.&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li data-path-to-node=&quot;7,0,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong data-path-to-node=&quot;7,0,0&quot; data-index-in-node=&quot;0&quot;&gt;Initial Dosing:&lt;/strong&gt; Start with a minimal amount and wait to gauge your body&#39;s reaction and tolerance before considering a second dose.&lt;/span&gt;&lt;/li&gt;
&lt;li data-path-to-node=&quot;7,1,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong data-path-to-node=&quot;7,1,0&quot; data-index-in-node=&quot;0&quot;&gt;Post-Abstinence Caution:&lt;/strong&gt; If you return to use after a break, you must use a significantly lower dose. Your previous &quot;normal&quot; dose could be fatal due to the loss of tolerance.&lt;/span&gt;&lt;/li&gt;
&lt;li data-path-to-node=&quot;7,2,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong data-path-to-node=&quot;7,2,0&quot; data-index-in-node=&quot;0&quot;&gt;Peer Advice:&lt;/strong&gt; Never rely on the dosage levels used by regular consumers. Their high tolerance means their typical dose could be lethal for a new or occasional user.&lt;/span&gt;&lt;/li&gt;
&lt;li data-path-to-node=&quot;7,3,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong data-path-to-node=&quot;7,3,0&quot; data-index-in-node=&quot;0&quot;&gt;Routine Breaks:&lt;/strong&gt; Maintain intervals of at least several days between uses to prevent dependency.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;High-Risk Administration and Interactions&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li data-path-to-node=&quot;10,0,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong data-path-to-node=&quot;10,0,0&quot; data-index-in-node=&quot;0&quot;&gt;Injection Risks:&lt;/strong&gt; Injecting opiates is highly discouraged due to the extreme risk of overdose and the difficulty in measuring the gap between a &quot;rush&quot; and a fatal dose. If you do inject, always use new, sterile equipment. Never share needles, filters, or water to prevent the transmission of HIV and hepatitis.&lt;/span&gt;&lt;/li&gt;
&lt;li data-path-to-node=&quot;10,1,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong data-path-to-node=&quot;10,1,0&quot; data-index-in-node=&quot;0&quot;&gt;Dietary Warnings:&lt;/strong&gt; Do not consume citrus fruits, especially &lt;strong data-path-to-node=&quot;10,1,0&quot; data-index-in-node=&quot;58&quot;&gt;grapefruit&lt;/strong&gt;, around the time of use. This combination can dangerously amplify the opiate&#39;s strength and lead to respiratory failure.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Mixed Use&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;span class=&quot;&quot;&gt;Combining two or more substances creates effects that are incredibly difficult to predict.&lt;/span&gt;&lt;span class=&quot;&quot;&gt; These interactions are rarely just a sum of their individual parts; instead,&lt;/span&gt;&lt;span class=&quot;&quot;&gt; mixing substances introduces unique and often severe health hazards.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Interactions with Depressants&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p data-path-to-node=&quot;5&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Combining codeine with other depressants, such as &lt;strong data-path-to-node=&quot;5&quot; data-index-in-node=&quot;49&quot;&gt;alcohol, ketamine, GHB/GBL, nitrous oxide, benzodiazepines, or other opioids,&amp;nbsp;&lt;/strong&gt;is extremely dangerous. This mixture significantly increases the likelihood of vomiting and slipping into unconsciousness. Because the body&#39;s protective reflexes are suppressed, there is a very high risk of &lt;strong data-path-to-node=&quot;5&quot; data-index-in-node=&quot;333&quot;&gt;suffocation&lt;/strong&gt;.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Interactions with Dissociatives and DXM&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li data-path-to-node=&quot;8,0,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong data-path-to-node=&quot;8,0,0&quot; data-index-in-node=&quot;0&quot;&gt;Methoxetamine (MXE):&lt;/strong&gt; Taking codeine alongside MXE can cause an unpredictable and dangerous intensification of the opioid&#39;s effects.&lt;/span&gt;&lt;/li&gt;
&lt;li data-path-to-node=&quot;8,1,0&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong data-path-to-node=&quot;8,1,0&quot; data-index-in-node=&quot;0&quot;&gt;DXM:&lt;/strong&gt; Mixing these is strongly discouraged, as it raises the risk of central nervous system disorders as well as heart and respiratory failure. Notably, DXM lowers your individual tolerance to opioids, making a standard dose potentially lethal.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;Mixing with Stimulants&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p data-path-to-node=&quot;11&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Using opiates in conjunction with stimulants like &lt;strong data-path-to-node=&quot;11&quot; data-index-in-node=&quot;50&quot;&gt;cocaine, amphetamine, or methamphetamine&lt;/strong&gt; places immense strain on the cardiovascular system. The opposing effects can mask one another, leading you to subjectively underestimate how intoxicated you are. A major danger occurs if the stimulant&#39;s effects wear off while the opiate is still active, which can result in a &lt;strong data-path-to-node=&quot;11&quot; data-index-in-node=&quot;367&quot;&gt;delayed overdose&lt;/strong&gt; and sudden respiratory depression.&lt;/span&gt;&lt;/p&gt;
&lt;p data-path-to-node=&quot;11&quot;&gt;&amp;nbsp;&lt;/p&gt;

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