&lt;h2&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;Overview&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Parental sample preparation for prenatal microarray testing involves obtaining blood samples from prospective parents. These samples are processed to extract DNA, which is then analyzed using microarray technology. This testing aids in identifying genetic abnormalities and assessing the risk of inherited disorders in the fetus. The results guide healthcare providers in offering appropriate counseling and making informed decisions regarding prenatal care and management.&lt;/span&gt;&lt;/p&gt;
&lt;hr /&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;WHAT IS IT USED FOR?&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;- Preparing parental blood samples for potential confirmation testing in case abnormalities are found in prenatal array samples.&lt;br /&gt;- Extracting DNA from maternal blood samples for maternal cell contamination testing.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;TESTING ALGORITHM&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;- This complimentary test facilitates correlation between proband and parental samples. If further testing is necessary, relevant tests will be conducted additionally.&lt;/span&gt;&lt;br /&gt;&lt;span style=&quot;color: #808080;&quot;&gt;- When ordering CMAP/Chromosomal Microarray for prenatal, amniotic fluid/chorionic villus sampling; CMAPC/Chromosomal Microarray for autopsy, products of conception, or stillbirth; or CMAMT/Chromosomal Microarray for autopsy/products of conception/stillbirth, tissue, parental blood samples are gathered and readied for confirmation studies if abnormalities are detected in the prenatal sample. Should abnormalities arise in the fetal sample, appropriate testing (microarray, FISH, or chromosome analysis) can be performed on parental specimens to aid prenatal result interpretation. While a paternal blood sample is requested, it&#39;s optional. Maternal cell contamination testing will be conducted on maternal blood and prenatal samples to rule out maternal cells in the fetal sample.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;METHOD NAME&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;DNA Extraction/&lt;a&gt;&lt;/a&gt;Cell Culture&lt;/span&gt;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;&lt;br /&gt;AVAILABILITY&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;TBC&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;REPORTING NAME&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Parental Prenatal Array Prep Test&lt;/span&gt;&lt;/p&gt;

&lt;h3 id=&quot;SpecimenType-title&quot;&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SPECIMEN TYPE&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;Whole blood&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SHIPPING INSTRUCTIONS&lt;br /&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;TBC&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SPECIMEN REQUIRED&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;strong&gt;This test requires 2 blood specimens: 1 sodium heparin and 1 EDTA&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;strong&gt;Specimen Type:&amp;nbsp;&lt;/strong&gt;Whole blood&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;strong&gt;Container/Tube:&lt;/strong&gt;&amp;nbsp;Green top (sodium heparin)&amp;nbsp;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;and&lt;/strong&gt;&lt;/span&gt;&amp;nbsp;lavender top (EDTA)&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;&lt;strong&gt;Specimen Volume:&lt;/strong&gt;&amp;nbsp;3 mL EDTA&amp;nbsp;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;and&lt;/strong&gt;&amp;nbsp;&lt;/span&gt;4 mL sodium heparin&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;Collection Instructions:&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;1. Invert several times to mix blood.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;2. Send whole blood specimens in the original tubes.&amp;nbsp;&lt;strong&gt;Do not aliquot.&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;SPECIMEN MINIMUM VOLUME&lt;/strong&gt;&amp;nbsp;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #808080;&quot;&gt;2 mL EDTA and 2 mL sodium heparin whole blood&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #33cccc;&quot;&gt;&lt;strong&gt;REJECT DUE TO&lt;/strong&gt;&amp;nbsp;&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;color: #808080;&quot;&gt;All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.&lt;/span&gt;&lt;/p&gt;

Parental Sample Prep for Prenatal Microarray Testing, Blood