&lt;h2&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;OVERVIEW&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;This prenatal test assesses the risk of Down syndrome and neural tube defects by combining an early ultrasound (to measure nuchal translucency) with a first-trimester blood test (for PAPP-A protein). If initial results indicate a high risk, a second-trimester blood test is available. Positive results lead to counseling and potentially additional testing.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Note: This test does not diagnose birth defects but identifies pregnancies that may require further evaluation.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;hr /&gt;
&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;TESTING ALGORITHM&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p data-sourcepos=&quot;3:1-3:78&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Sequential screening is a two-part prenatal test for Down syndrome risk.&lt;/span&gt;&lt;/p&gt;
&lt;ul data-sourcepos=&quot;5:1-5:16&quot;&gt;
&lt;li data-sourcepos=&quot;5:1-5:16&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;The first part involves an ultrasound to measure nuchal translucency (fluid collection at the back of the fetal neck) and a blood test in the first trimester.&lt;/span&gt;&lt;/li&gt;
&lt;li data-sourcepos=&quot;6:1-6:1&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;If the first-trimester results suggest a higher Down syndrome risk, the screening is completed.&lt;/span&gt;&lt;/li&gt;
&lt;li data-sourcepos=&quot;7:1-7:46&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;If the first-trimester results are negative, a second blood test is needed in the second trimester.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p data-sourcepos=&quot;9:1-9:91&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Not completing the second part (SEQB) means no overall risk assessment can be provided.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;METHOD NAME&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Immunoenzymatic&amp;nbsp;Assay&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;AVAILABILITY&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;TBC&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;REPORTING NAME&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Sequential Maternal Screen, Part 1&lt;/span&gt;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong&gt;&lt;br /&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;ALIASES&lt;/span&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;div class=&quot;container&quot;&gt;
&lt;div class=&quot;row&quot;&gt;
&lt;div class=&quot;col-12 col-sm-12 col-md-12&quot;&gt;
&lt;div class=&quot;tab-component&quot;&gt;
&lt;div class=&quot;tab-content-wrapper&quot;&gt;
&lt;div id=&quot;tabcontent-Overview&quot; class=&quot;tab-content-item active&quot;&gt;
&lt;div id=&quot;aliases-value&quot;&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Maternal Serum Sequential Screen&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Sequential Screening&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Serum Stepwise Sequential Screen&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Stepwise Maternal Screen&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Stepwise Sequential&lt;/span&gt;&lt;/p&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3 id=&quot;SpecimenType-title&quot;&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;SPECIMEN TYPE&lt;/strong&gt;&amp;nbsp;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Serum&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;SHIPPING INSTRUCTIONS&lt;/span&gt;&lt;br /&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;TBC&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;SPECIMEN REQUIRED&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;ul&gt;
&lt;li data-sourcepos=&quot;3:1-3:81&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong&gt;Blood collection tube:&lt;/strong&gt; Ideally use a serum gel tube (preferred), but a red top tube is also okay.&lt;/span&gt;&lt;/li&gt;
&lt;li data-sourcepos=&quot;4:1-4:112&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong&gt;Timing:&lt;/strong&gt; The ultrasound and blood test must be done within a specific pregnancy window (10 weeks 0 days to 13 weeks 6 days) when the fetus measures 31 to 80 mm (crown-rump length).&lt;/span&gt;&lt;/li&gt;
&lt;li data-sourcepos=&quot;5:1-5:25&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong&gt;After collection:&lt;/strong&gt; Spin the blood in a centrifuge (centrifuge) within 2 hours. Then, carefully transfer only the liquid part (serum) into a plastic vial, using 1 milliliter (mL).&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;

SS grp 3 digitize glass slide, Thailand

SS grp 2 digitize glass slide, Thailand

Sequential Maternal Screening, Part 1, Serum