&lt;h2&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;OVERVIEW&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;The SEQA prenatal test is a two-part screening for Down syndrome and neural tube defects (NTDs).&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;In the first part, an ultrasound measures nuchal translucency (fluid at the back of the fetal neck) and a blood test checks pregnancy-associated protein A (PAPP-A) during the first trimester. If these results indicate an increased risk for Down syndrome, a second blood test in the second trimester is conducted. This test measures alpha-fetoprotein (AFP), unconjugated estriol (uE3), human chorionic gonadotropin (hCG), and inhibin A.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;The combined results from both tests help estimate the risk of Down syndrome. Positive results lead to counseling and possibly further testing.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;hr /&gt;
&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;TESTING ALGORITHM&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p data-sourcepos=&quot;3:1-3:78&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Sequential screening is a two-part prenatal test for Down syndrome risk.&lt;/span&gt;&lt;/p&gt;
&lt;ul data-sourcepos=&quot;5:1-5:16&quot;&gt;
&lt;li data-sourcepos=&quot;5:1-5:16&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;The first part involves an ultrasound to measure nuchal translucency (fluid collection at the back of the fetal neck) and a blood test in the first trimester.&lt;/span&gt;&lt;/li&gt;
&lt;li data-sourcepos=&quot;6:1-6:1&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;If the first-trimester results suggest a higher Down syndrome risk, the screening is completed.&lt;/span&gt;&lt;/li&gt;
&lt;li data-sourcepos=&quot;7:1-7:46&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;If the first-trimester results are negative, a second blood test is needed in the second trimester.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p data-sourcepos=&quot;9:1-9:91&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Not completing the second part (SEQB) means no overall risk assessment can be provided.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;METHOD NAME&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Immunoenzymatic Assay&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;AVAILABILITY&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;TBC&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;REPORTING NAME&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Sequential Maternal Screen, Part 2&lt;/span&gt;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong&gt;&lt;br /&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;ALIASES&lt;/span&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;div class=&quot;container&quot;&gt;
&lt;div class=&quot;row&quot;&gt;
&lt;div class=&quot;col-12 col-sm-12 col-md-12&quot;&gt;
&lt;div class=&quot;tab-component&quot;&gt;
&lt;div class=&quot;tab-content-wrapper&quot;&gt;
&lt;div id=&quot;tabcontent-Overview&quot; class=&quot;tab-content-item active&quot;&gt;
&lt;div id=&quot;aliases-value&quot;&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Maternal Serum Sequential Screen&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Sequential Screening&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Serum Stepwise Sequential Screen&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Stepwise Maternal Screen&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Stepwise Sequential&lt;/span&gt;&lt;/p&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3 id=&quot;SpecimenType-title&quot;&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;SPECIMEN TYPE&lt;/strong&gt;&amp;nbsp;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Serum&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;SHIPPING INSTRUCTIONS&lt;/span&gt;&lt;br /&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;TBC&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;SPECIMEN REQUIRED&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;ul&gt;
&lt;li data-sourcepos=&quot;3:1-3:69&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong&gt;Blood collection tube:&lt;/strong&gt; Ideally use a serum gel tube (preferred), but a red top tube is also okay.&lt;/span&gt;&lt;/li&gt;
&lt;li data-sourcepos=&quot;4:1-4:65&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong&gt;Timing:&lt;/strong&gt; Collect blood between 15 weeks and 22 weeks 6 days of pregnancy. Avoid collecting blood after an amniocentesis, as it can alter test results.&lt;/span&gt;&lt;/li&gt;
&lt;li data-sourcepos=&quot;5:1-5:44&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong&gt;After collection:&lt;/strong&gt; Spin the blood in a centrifuge (centrifuge) within 2 hours. Then, carefully transfer only the liquid part (serum) into a plastic vial, using 1 milliliter (mL).&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;

SS grp 3 digitize glass slide, Thailand

SS grp 2 digitize glass slide, Thailand

Sequential Maternal Screening, Part 2, Serum