&lt;h2&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;OVERVIEW&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Alpha-1 antitrypsin (AAT) is a liver-produced protein that helps protect the lungs from damage. AAT deficiency, a genetic disorder prevalent among Northern Europeans, leads to emphysema (particularly in the lower lungs) in adults and liver disease in children. Symptoms such as cough, wheezing, and breathing difficulties often develop in the 30s or 40s and may be mistakenly diagnosed as asthma.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Diagnosis of AAT deficiency involves blood tests and genetic analysis. The combination of S and Z gene variations raises the risk of emphysema, while the ZZ combination increases the risk of both emphysema and liver disease. Smoking exacerbates the condition, and newer tests can detect rare mutations beyond the common ones.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;hr /&gt;
&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;METHOD NAME&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Polymerase Chain Reaction (PCR) Amplification/DNA Sequencing&lt;/span&gt;&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;AVAILABILITY&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;TBC&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;REPORTING NAME&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;SERPINA1 Gene, Full Gene Analysis&lt;/span&gt;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong&gt;&lt;br /&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;ALIASES&lt;/span&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;div class=&quot;container&quot;&gt;
&lt;div class=&quot;row&quot;&gt;
&lt;div class=&quot;col-12 col-sm-12 col-md-12&quot;&gt;
&lt;div class=&quot;tab-component&quot;&gt;
&lt;div class=&quot;tab-content-wrapper&quot;&gt;
&lt;div id=&quot;tabcontent-Overview&quot; class=&quot;tab-content-item active&quot;&gt;
&lt;div id=&quot;aliases-value&quot;&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;A1ATM&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;A1AT&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;AATD&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Alpha-1 Antitrypsin Deficiency&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Serpin Peptidase Inhibitor, Clade A, Member 1&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;AAT Deficiency&lt;/span&gt;&lt;/p&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

&lt;h3&gt;&amp;nbsp;&lt;/h3&gt;
&lt;h3 id=&quot;SpecimenType-title&quot;&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;&lt;strong&gt;SPECIMEN TYPE&lt;/strong&gt;&amp;nbsp;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Varies&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong&gt;&lt;span style=&quot;color: #ff99cc;&quot;&gt;SHIPPING INSTRUCTIONS&lt;/span&gt;&lt;br /&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;TBC&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;strong style=&quot;color: #ff99cc;&quot;&gt;SPECIMEN REQUIRED&lt;/strong&gt;&lt;/h3&gt;
&lt;p&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;&lt;strong&gt;Blood collection:&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul data-sourcepos=&quot;5:5-5:51&quot;&gt;
&lt;li data-sourcepos=&quot;5:5-5:51&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Tube: Lavender top (EDTA) or yellow top (ACD) preferred, any anticoagulant acceptable.&lt;/span&gt;&lt;/li&gt;
&lt;li data-sourcepos=&quot;6:5-6:19&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;Amount: 3 mL.&lt;/span&gt;&lt;/li&gt;
&lt;li data-sourcepos=&quot;7:5-7:62&quot;&gt;&lt;span style=&quot;color: #99ccff;&quot;&gt;After collection: Invert tube to mix blood, then send it in the original tube.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;

SS grp 3 digitize glass slide, Thailand

SS grp 2 digitize glass slide, Thailand

SERPINA1 Gene, Full Gene Analysis, Varies